Tangential flow filtration (TFF) is a basic operating unit in biopharmacological processes. Combined with hollow fiber components or plate-coated filters with different molecular weight cutoff (MWCO)/pore sizes, TFF can be used for harvesting, concentration, washing and filtration of various products, or buffer displacement.
The ARM tangential flow filtering system adopts fully integrated and intelligent design, which can complete different process operation modes with high compatibility. Combined with perfect process monitoring components and parameter recording/control software, it can truly realize the tangential flow filtering operation without supervision.
Product Features:
· Fully integrated: integrated with feed peristaltic pump, auxiliary peristaltic pump, control & data collection software, pressure & flowrate monitoring and backpressure control, no need for additional components;
· Fully automatic: automatically switch between concentration and diafiltration steps based on process setpoint through software control, and process sequence can be freely user-defined;
· Flexibility: perfectly match with modern single-use and closed bioprocessing concept, avoiding cross-contamination and cleaning with disposable pressure sensor and non-invasive ultrasonic flowmeter, ensuring flexibility;
· Compatibility: Compatible with filters from different suppliers, just input key specifications, process parameters including shear rate and flux can be calculated;
· Scalability: same mechanical principle with pilot and production systems, scaling-up can be achieved according to main pump output flowrate, meeting requirements of filter with various sizes;
· Compliance: GMP compliant software and hardware design, can be used for small scale production in gene/cell therapy.

AMR1-15 Research Scale TFF System
Item | Specification |
Max. process volume | Up to 10 L |
Min. running volume | 2 ml (depends tube size and connection) |
Filter SA | Up to >1.0 m2 (depends on crossflow required) |
Main driver/feed pump | Compatible with #13-#18 tube,max up to 2.3 L/min |
Auxiliary pump | Compatible with #16, #25 tube,up to324 ml/min |
Pressure sensor | 3 disposable pressure sensors (0-60psi) |
TMP & Permeate pressure control | Non-invasive automatic backpressure control valve*2 |
Flowmeter | Non-invasive Flowmeter |
Conductivity sensor | 0.1 -100mS/cm |
Control & Monitor | 13.3”LCD Touch Screen |
Software | 8 auto modes, complete parameter record, compliant with GMP requirements |
Extension components | Scales, auxiliary pumps and others |

AMR2-15 Polit TFF System
Item | Specification |
Max. process volume | Up to 200 L |
Min. running volume | 300 ml (depends tube size and connection) |
Filter SA | Up to >5.0 m2 (depends on crossflow required) |
Main driver/feed pump | Compatible with #26-#82 tube,max up to 13 L/min |
Auxiliary pump | Compatible with #16-#18 tube,up to2.3 ml/min |
Pressure sensor | 3 disposable pressure sensors (0-60psi) |
TMP & Permeate pressure control | Non-invasive automatic backpressure control valve*2 |
Flowmeter | Non-invasive Flowmeter |
Conductivity sensor | 0.1 -100mS/cm |
Control & Monitor | 15.6”LCD Touch Screen |
Software | 8 auto modes, complete parameter record, compliant with GMP requirements |
Extension components | Scales, auxiliary pumps and others |
Please call 139 1004 3340 or service@whaleintelli.com for further product details.