Whaleintelli hollow fiber filter is mainly made of (modified) polyether sulfone, which has the advantages of good chemical compatibility, low non-specific adsorption and high filtration flux. It is widely used in biomedical and food and beverage fields.

Main Applications：

· Recombinant Protein: Harvest, purification and concentration of recombinant proteins from E.coli, yeast and mammalian cells, including insulins, GLP-1 and collagen；

· Antibody: Concentration and diafiltration of monoclonal antibody, bispecific antibody, antibody-drug conjugates (ADC) and antibody fragments；

· Cell therapy: Harvest, concentration and buffer exchange of T cell, NK cell, induced pluripotent stem cell (iPSC), and mesenchymal stem cell (MSC)；

· Gene therapy:Concentration of virus vectors (Lentivirus (LV), Adeno-associated virus (AAV)) and oncolytic virus;

· Gene therapy:Concertation and buffer exchange of nucleic acid (plasmid DNA, mRNA and siRNA);

· Gene therapy:Concentration and diafiltration of delivery vector (Lipid nanoparticles);

· Gene therapy:Harvest, concentration and diafiltration of extracellular vesicles/exosomes.

· Vaccine:Concentration and buffer exchange of virus, virus vectors and virus-like particles based vaccines;

· Vaccine:Harvest and purification of rProtein-based vaccine antigen;

· Vaccine:Manufacturing of nucleic acid-based vaccines;

· Vaccine:Preparation and purification of novel adjuvants.

Product Features：

· Complete pore size /MWCO specifications: ultrafiltration 3 kd-750 kD; Microfiltration 0.1 μm - 0.65 μm;

· Wide membrane surface area ensures that the process can be scaled up from R&D to production Scale: 26 cm2-16.6 m2;

· A variety of fiber inner diameters can be selected to meet the processing requirements of different viscosity liquid: 0.5 mm-2 mm;

· Broad chemical compatibility, high hydrophilicity, low non-specific adsorption, effectively reduce the process of membrane blockage, improve the filtration flux;

· The component materials are Free of animal-derived components and meet the USP grade VI requirements: TSE/BSE Free;

· Strict quality control ensures batch to batch consistency: no fiber and particulate matter shedding, 100% integrity testing.

HF Part Number

Note: M20-P100-05-N in the figure represents: the length of the normal hollow fiber filter component is 20cm, and the PES filter material with inner diameter of 0.5mm and MWCO of 100KD is used.

Please call 139 1004 3340 or service@whaleintelli.com for further product details.